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Immp2lTg(Tyr)979Ove
Transgenic Allele Detail
Summary
Symbol: Immp2lTg(Tyr)979Ove
Name: IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae); transgene insertion 979, Paul A Overbeek
MGI ID: MGI:3765965
Synonyms: Immp2lTg(Tyr)979OB
Gene: Immp2l  Location: Chr12:41074089-42002371 bp, + strand  Genetic Position: Chr12, 18.69 cM, cytoband B3
Alliance: Immp2lTg(Tyr)979Ove page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 5.5 kb fragment containing the LTR-Tyr expression cassette was injected into homozygous FVB/N fertilized eggs. A 50 kb deletion within the sixth intron was associated with the transgene insertion. A truncated mRNA containing just the first 6 exons was the only mRNA detected by RT-PCR. (J:128071)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Immp2l Mutation:  27 strains or lines available
References
Original:  J:128071 Lu B, et al., A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Biol Reprod. 2008 Apr;78(4):601-10
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory