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Sema3btm1Mom
Targeted Allele Detail
Summary
Symbol: Sema3btm1Mom
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; targeted mutation 1, Peter Mombearts
MGI ID: MGI:3758884
Synonyms: deltaB
Gene: Sema3b  Location: Chr9:107474873-107486428 bp, - strand  Genetic Position: Chr9, 58.31 cM
Alliance: Sema3btm1Mom page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125485
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll of the open reading frame, exons 1-17, were replaced with the ACNF cassette, which self-excised upon germline transmission leaving a null allele. (J:125485)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3b Mutation:  31 strains or lines available
References
Original:  J:125485 Walz A, et al., Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F. Development. 2007;134:4063-72
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory