Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxp2tm1.2Sfis
Name:	forkhead box P2; targeted mutation 1.2, Simon E Fisher
MGI ID:	MGI:3723630
Synonyms:	Foxp2delta12-14
Gene:	Foxp2  Location: Chr6:14901348-15441976 bp, + strand  Genetic Position: Chr6, 6.49 cM, cytoband A2
Alliance:	Foxp2tm1.2Sfis page

Germline Transmission:	Earliest citation of germline transmission: J:125023
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 12 through 14 were removed by cre-mediated recombination. The absence of protein product was confirmed by western blot analysis on the striatal precursor region of E16.5 embryos using antibodies recognizing the N-terminal region of the protein. (J:125023)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp2 Mutation:	52 strains or lines available

Original:	J:125023 French CA, et al., Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6
All:	2 reference(s)