Summary | Transgene origin | Transgene description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Col2a1-Npr2*B2)25-4Gar
Name:	transgene insertion 25-4, David L Garbers
MGI ID:	MGI:3722765
Synonyms:	GCB2-Tgm, Tg(Col2a1-Npr2)254Gar, Tg(Col2a1-Npr2)25-4Gar
Transgene:	Tg(Col2a1-Npr2*B2)25-4Gar  Location: unknown
Alliance:	Tg(Col2a1-Npr2*B2)25-4Gar page

Strain of Origin:

C57BL/6 and SJL

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Col2a1-Npr2*B2)25-4Gar expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Npr2 (MGI:97372)   Mutation details: A transgenic B-geo expression construct incorporating the GC-B2 isoform of the mouse gene (expressed in growth-plate chondrocytes) driven by the mouse Col2a1 (procollagen, type II, alpha 1) promoter/enhancer was generated for microinjection. Lin 25-4 was developed. (J:94718)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:94718 Tamura N, et al., Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17300-5
All:	1 reference(s)