Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trpc2tm2Mom
Name:	transient receptor potential cation channel, subfamily C, member 2; targeted mutation 2, Peter Mombaerts
MGI ID:	MGI:3722352
Synonyms:	Trpc2-IRES-taumCherry
Gene:	Trpc2  Location: Chr7:101732323-101745603 bp, + strand  Genetic Position: Chr7, 54.71 cM, cytoband F1
Alliance:	Trpc2tm2Mom page

Germline Transmission:	Earliest citation of germline transmission: J:218085
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: An IRES-taumCherry cassette, along with self-excising ACNF selection cassette, was inserted 32 base pairs downstream of the STOP codon of the endogenous coding sequence so that the taumCherry fusion protein is co-expressed to mark endogenous gene expression. (J:218085)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trpc2 Mutation:	98 strains or lines available

Original:	J:218085 Omura M, et al., Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol Cell Neurosci. 2015 Mar;65:114-24
All:	5 reference(s)