Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atf7tm1Nicj
Name:	activating transcription factor 7; targeted mutation 1, Nic Jones
MGI ID:	MGI:3720869
Synonyms:	Atf7-
Gene:	Atf7  Location: Chr15:102434381-102533899 bp, - strand  Genetic Position: Chr15, 57.66 cM, cytoband F3
Alliance:	Atf7tm1Nicj page

Germline Transmission:	Earliest citation of germline transmission: J:123909
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to insert an IRES-lacZ-pA and floxed neo into the locus, replacing part of exon 10 which encodes the basic region DNA binding domain and part of the leucine zipper dimerization domain. (J:123909)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atf7 Mutation:	61 strains or lines available

Original:	J:123909 Breitwieser W, et al., Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells. Genes Dev. 2007 Aug 15;21(16):2069-82
All:	3 reference(s)