Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Del(11Cxcl16-Zmynd15)1Ifc Name: deletion, Chr 11, Israel F Charo MGI ID: MGI:3720171 Synonyms: Cxcl16-, Cxcl16tm1Ifc, Cxcl16/Zmynd15tm1Ifc Gene: Del(11Cxcl16-Zmynd15)1Ifc  Location: unknown  Genetic Position: Chr11, Syntenic

Spermatogenic disruption in the testes of Del(11Cxcl16-Zmynd15)1Ifc/Del(11Cxcl16-Zmynd15)1Ifc mice Show the 4 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:123851
Parent Cell Line:	RF8 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion, Intragenic deletion   Del(11Cxcl16-Zmynd15)1Ifc involves 2 genes/genome features (Cxcl16, Zmynd15) View all   Mutation details: A neomycin resistance cassette replaced the entire coding sequence of Cxcl16 and a portion of the overlapping 5'UTR of Zmynd15. Quantitative RT-PCR confirmed the absence of both transcripts. (J:123851)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(11Cxcl16-Zmynd15)1Ifc Mutation:	0 strains or lines available

Original:	J:123851 Aslanian AM, et al., Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerosis. Circulation. 2006 Aug 8;114(6):583-90
All:	2 reference(s)