About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:121776 Li B, et al., Developmental phenotypes and reduced Wnt signaling in mice deficient for pygopus 2. Genesis. 2007 May;45(5):318-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3716615
Gene symbol: Pygo2
Gene name: pygopus 2
Antibody: anti-Pygo2
Detection system: Secondary antibody
Results
Specimen 2a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hair follicle Present Regionally restricted 2a Expression of nuclear protein in epithelial cells of the presumptive bulge and matrix/precortex of pelage hair follicles. Expression also in dermal cells adjacent to these epithelial compartments.

Specimen 2b: embryonic day 18.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS26: hair follicle Absent 2b

Specimen 2c: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vibrissa Present Regionally restricted 2c Expression of nuclear protein epithelial cells in outer root sheath of whisker follicles.

Specimen 2d: embryonic day 18.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS26: vibrissa Absent 2d

Specimen 2e: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bronchiole epithelium Strong Regionally restricted 2e Strong nuclear expression in a subset of epithelial cells lining the larger terminal airways.
TS26: lung epithelium Present Spotted 2e Scattered expressing cells also in epithelium of smaller, peripheral terminal airways and in the mesenchyme.
TS26: lung mesenchyme Present Spotted 2e Scattered expressing cells also in epithelium of smaller, peripheral terminal airways and in the mesenchyme.

Specimen 2f: embryonic day 18.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS26: lung Absent 2f

Specimen 2g: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: intestine epithelium Weak Regionally restricted 2g Weak, but detectable, expression in intestinal villous epithelial cells, and in a subset of mesenchymal cells.
TS26: intestine mesenchyme Weak Regionally restricted 2g Weak, but detectable, expression in intestinal villous epithelial cells, and in a subset of mesenchymal cells.

Specimen 2h: embryonic day 18.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS26: intestine Absent 2h


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory