Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:121776
Li B, et al., Developmental phenotypes and reduced Wnt signaling in mice deficient for pygopus 2. Genesis. 2007 May;45(5):318-25
|
Assay type:
|
Immunohistochemistry
|
MGI Accession ID:
|
MGI:3716615
|
Gene symbol:
|
Pygo2
|
Gene name:
|
pygopus 2
|
Antibody:
|
anti-Pygo2
|
Detection system:
|
Secondary antibody
|
|
Results
|
Specimen
2a:
embryonic day 18.5
(more )
Specimen
2a:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: hair follicle |
Present |
Regionally restricted |
2a
|
Expression of nuclear protein in epithelial cells of the presumptive bulge and matrix/precortex of pelage hair follicles. Expression also in dermal cells adjacent to these epithelial compartments.
|
Specimen
2b:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6
|
Mutant Allele(s):
|
Pygo2tm1.2Xdai/Pygo2tm1.2Xdai
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Specimen
2c:
embryonic day 18.5
(more )
Specimen
2c:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: vibrissa |
Present |
Regionally restricted |
2c
|
Expression of nuclear protein epithelial cells in outer root sheath of whisker follicles.
|
Specimen
2d:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6
|
Mutant Allele(s):
|
Pygo2tm1.2Xdai/Pygo2tm1.2Xdai
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Specimen
2e:
embryonic day 18.5
(more )
Specimen
2e:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: bronchiole epithelium |
Strong |
Regionally restricted |
2e
|
Strong nuclear expression in a subset of epithelial cells lining the larger terminal airways.
|
TS26: lung epithelium |
Present |
Spotted |
2e
|
Scattered expressing cells also in epithelium of smaller, peripheral terminal airways and in the mesenchyme.
|
TS26: lung mesenchyme |
Present |
Spotted |
2e
|
Scattered expressing cells also in epithelium of smaller, peripheral terminal airways and in the mesenchyme.
|
Specimen
2f:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6
|
Mutant Allele(s):
|
Pygo2tm1.2Xdai/Pygo2tm1.2Xdai
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Specimen
2g:
embryonic day 18.5
(more )
Specimen
2g:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: intestine epithelium |
Weak |
Regionally restricted |
2g
|
Weak, but detectable, expression in intestinal villous epithelial cells, and in a subset of mesenchymal cells.
|
TS26: intestine mesenchyme |
Weak |
Regionally restricted |
2g
|
Weak, but detectable, expression in intestinal villous epithelial cells, and in a subset of mesenchymal cells.
|
Specimen
2h:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6
|
Mutant Allele(s):
|
Pygo2tm1.2Xdai/Pygo2tm1.2Xdai
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Fixation:
|
Bouin's Fixative
|
Embedding:
|
Paraffin
|
|