Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1Mom
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Peter Mombaerts
MGI ID:	MGI:3712829
Synonyms:	ROSA26-STOP-taulacZ
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1Mom page

Germline Transmission:	Earliest citation of germline transmission: J:237335
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: A splice acceptor containing Asc1 (CTAGTTCCCTTTTTTTTCACAG-GTTGGCGCGCCACGGTGATC) was inserted in the Nhe site of the intron of Gt(ROSA)26Sor, and then, into the Asc1 site, a sequence containing Asc1-loxP-CAT-pA-loxP-tauLacZ-betaGlobinpA-FRT-Neo-FRT-Asc1 was inserted to generate this allele with a loxP-flanked STOP sequence just upstream of tauLacZ. (J:237335)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:237335 Lin J, et al., Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. Sci Rep. 2016 Dec 19;6:39457
All:	1 reference(s)