Gt(ROSA)26Sortm1Mom
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1Mom |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Peter Mombaerts |
MGI ID: |
MGI:3712829 |
Synonyms: |
ROSA26-STOP-taulacZ |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1Mom page
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Germline Transmission: |
Earliest citation of germline transmission:
J:237335
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, Reporter) |
Mutation: |
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Insertion
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Mutation details: A splice acceptor containing Asc1 (CTAGTTCCCTTTTTTTTCACAG-GTTGGCGCGCCACGGTGATC) was inserted in the Nhe site of the intron of Gt(ROSA)26Sor, and then, into the Asc1 site, a sequence containing Asc1-loxP-CAT-pA-loxP-tauLacZ-betaGlobinpA-FRT-Neo-FRT-Asc1 was inserted to generate this allele with a loxP-flanked STOP sequence just upstream of tauLacZ.
(J:237335)
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Original: |
J:237335 Lin J, et al., Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. Sci Rep. 2016 Dec 19;6:39457 |
All: |
1 reference(s) |
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