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Ccl7tm1Ifc
Targeted Allele Detail
Summary
Symbol: Ccl7tm1Ifc
Name: C-C motif chemokine ligand 7; targeted mutation 1, Israel F Charo
MGI ID: MGI:3712065
Synonyms: Mcp-3-
Gene: Ccl7  Location: Chr11:81936538-81938351 bp, + strand  Genetic Position: Chr11, 49.83 cM
Alliance: Ccl7tm1Ifc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121281
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector containing a neomycin resistance cassette was inserted to replace the coding sequence. (J:121281)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccl7 Mutation:  12 strains or lines available
References
Original:  J:121281 Tsou CL, et al., Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest. 2007 Apr;117(4):902-9
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory