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Gene Expression Data
Assay Details
Assay
Reference: J:73085 Dasen JS, et al., Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207
Assay type: RNA in situ
MGI Accession ID: MGI:3711475
Gene symbol: Lhx3
Gene name: LIM homeobox protein 3
Probe: Lhx3 probe3
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1D e12.5: embryonic day 12.5; Hesx1tm1Icar/Hesx1tm1Icar (more )
Structure Level Pattern Image Note
TS20: adenohypophysis Trace 1D Lhx3 There is a rudimentary pouch formed which contains minimal expression.

Specimen 1F e12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis Present 1F Wt

Specimen 2E e10.5 wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 2E e10.5 +/+

Specimen 2E e10.5 Hesx1(-/-): embryonic day 10.5; Hesx1tm1Icar/Hesx1tm1Icar (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 2E e10.5 -/- Expression is expanded rostrally in the mutant.

Specimen 2E e12.5 wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis Present 2E e12.5 +/+

Specimen 2E e12.5 Hesx1(-/-): embryonic day 12.5; Hesx1tm1Icar/Hesx1tm1Icar (more )
Structure Level Pattern Image Note
TS20: adenohypophysis Present 2E e12.5 -/- Expression is expanded rostrally in the mutant.

Specimen 6D e16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: pituitary gland Present 6D Lhx3 wt

Specimen 6E e16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: pituitary gland Present 6E Lhx3 wt


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory