Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mesp2tm7(mespb)Ysa
Name:	mesoderm posterior 2; targeted mutation 7, Yumiko Saga
MGI ID:	MGI:3702191
Synonyms:	neo-mespb
Gene:	Mesp2  Location: Chr7:79460475-79463179 bp, + strand  Genetic Position: Chr7, 45.18 cM
Alliance:	Mesp2tm7(mespb)Ysa page

Germline Transmission:	Earliest citation of germline transmission: J:75945
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Inserted expressed sequence, Null/knockout) Mutation:    Insertion   Mesp2tm7(mespb)Ysa expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note zebrafish mespba (58070) Mesp1  (MGI:107785) Mesp2  (MGI:1096325)   Mutation details: The mouse gene was replaced with the open reading frame of zebrafish mespb followed by a floxed-neo cassette. (J:75945)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mesp2 Mutation:	30 strains or lines available

Original:	J:75945 Nomura-Kitabayashi A, et al., Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis. Development. 2002 May;129(10):2473-81
All:	1 reference(s)