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Tg(Ins2-Cd274)2Mdos
Transgene Detail
Summary
Symbol: Tg(Ins2-Cd274)2Mdos
Name: transgene insertion 2, H Michael Dosch
MGI ID: MGI:3701452
Synonyms: RIP-B7H1, RIP-PDL1L
Transgene: Tg(Ins2-Cd274)2Mdos  Location: unknown  
Alliance: Tg(Ins2-Cd274)2Mdos page
Transgene
origin
Strain of Origin:  NOD/ShiLt
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ins2-Cd274)2Mdos expresses 1 gene
 
Tg(Ins2-Cd274)2Mdos expression driven by 1 gene
 
Mutation detailsThis transgene contains cDNA encoding human CD274 (B7H1) fused to the rat insulin 2 promoter. Transgenic mice express CD274 in pancreatic beta cells. (J:118934)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:118934 Tang L, et al., Non-obese diabetic mice overexpressing CD274 in pancreatic beta cells have an accelerated diabetes phenotype. MGI Direct Data Submission. 2007;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory