Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Apbb1tm1Trus
Name:	amyloid beta precursor protein binding family B member 1; targeted mutation 1, Tommaso Russo
MGI ID:	MGI:3699106
Synonyms:	Fe65-, Fe65 KO
Gene:	Apbb1  Location: Chr7:105207690-105230860 bp, - strand  Genetic Position: Chr7, 55.9 cM
Alliance:	Apbb1tm1Trus page

Germline Transmission:	Earliest citation of germline transmission: J:118164
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exon 2 was replaced with a PGK-neo cassette. (J:118164)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apbb1 Mutation:	51 strains or lines available

Original:	J:118164 Minopoli G, et al., Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage. J Biol Chem. 2007 Jan 12;282(2):831-5
All:	3 reference(s)