Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Prnp-APP)A-2Dbo
Name:	transgene insertion A-2, David R Borchelt
MGI ID:	MGI:3696803
Transgene:	Tg(Prnp-APP)A-2Dbo  Location: unknown
Alliance:	Tg(Prnp-APP)A-2Dbo page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(Prnp-APP)A-2Dbo expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human APP (351) App  (MGI:88059)   Mutation details: Mice with this transgene express the human amyloid precursor protein (APP) under control of the mouse prion protein promoter. (J:117538)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:117538 Borchelt DR, Transgenic mice expressing human amyloid precursor protein under the control of the mouse prion protein promoter. MGI Direct Data Submission. 2007;
All:	1 reference(s)