Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Asf1bGt(ROSABetageo)437Muv
Name:	anti-silencing function 1B histone chaperone; gene trap 437, Muriel Vernet
MGI ID:	MGI:3696542
Gene:	Asf1b  Location: Chr8:84682323-84696824 bp, + strand  Genetic Position: Chr8, 40.22 cM
Alliance:	Asf1bGt(ROSABetageo)437Muv page

Germline Transmission:	Earliest citation of germline transmission: J:82809
Parent Cell Line:	AT1 (ES Cell)
Strain of Origin:	129S2/SvPasCrl

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: Embryonic stem cells were infected with the retroviral gene trap vector ROSABetageo, which contains a splice acceptor site joined to the Betageo (lacZ-neomycin resistance) fusion gene. The trapped gene was inactivated by integration of the vector. Tissue-specific beta-galactosidase activity has been demonstrated by X-gal staining in neural tissues of developing embryos by embryonic day 8.5 (E8.5) and in gonocytes of E15 female embryos. Expression is also observed in the male gonad by postnatal day 8; it is restricted to pachytene spermatocytes in the adult male. (J:82809)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Asf1b Mutation:	20 strains or lines available

Original:	J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:	2 reference(s)