Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il10tm1Flv
Name:	interleukin 10; targeted mutation 1, Richard A Flavell
MGI ID:	MGI:3695482
Synonyms:	IL-10-GFP tiger, Il-10-IRES-GFP, tiger
Gene:	Il10  Location: Chr1:130947582-130952711 bp, + strand  Genetic Position: Chr1, 56.89 cM
Alliance:	Il10tm1Flv page

Germline Transmission:	Earliest citation of germline transmission: J:116616
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (No functional change, Reporter) Mutation:    Insertion   Mutation details: A targeting vector containing IRES-GFP was inserted into the locus between the stop codon and the polyA signal in exon 5. A floxed neo was removed via cre mediated recombination. (J:116616)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Il10 Mutation:	44 strains or lines available

Original:	J:116616 Kamanaka M, et al., Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity. 2006 Dec;25(6):941-52
All:	106 reference(s)