Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nasptm1Mgor
Name:	nuclear autoantigenic sperm protein (histone-binding); targeted mutation 1, Michael G O'Rand
MGI ID:	MGI:3694795
Synonyms:	Nasp-
Gene:	Nasp  Location: Chr4:116458249-116485138 bp, - strand  Genetic Position: Chr4, 53.24 cM, cytoband D1
Alliance:	Nasptm1Mgor page

Germline Transmission:	Earliest citation of germline transmission: J:116454
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Six exons were removed from the locus, resulting in the loss of amino acid residues 100-605 in the tNASP sequence and amino acid residues 74-253 in the sNASP sequence. (J:116454)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nasp Mutation:	55 strains or lines available

Original:	J:116454 Richardson RT, et al., Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation. J Biol Chem. 2006 Jul 28;281(30):21526-34
All:	1 reference(s)