Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Ins2-Ccl21b)2Cys
Name:	transgene insertion 2, Jason G Cyster
MGI ID:	MGI:3689181
Synonyms:	RIP-CCL21, RIP-SLC
Transgene:	Tg(Ins2-Ccl21b)2Cys  Location: unknown
Alliance:	Tg(Ins2-Ccl21b)2Cys page

Strain of Origin:

(C57BL/6 x DBA/2)F1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Ins2-Ccl21b)2Cys expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Ccl21b (MGI:1349182)   Tg(Ins2-Ccl21b)2Cys expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note rat Ins2 (24506) Ins2  (MGI:96573)   Mutation details: A full-length cDNA of murine Ccl21b was inserted into a construct containing the promoter/enhancer intron region (RIP7) of the rat insulin promoter 2. The resulting transgenic line II (2) contains 4 copies of the transgene and was used for further analyses. (J:77238)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:77238 Luther SA, et al., Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J Immunol. 2002 Jul 1;169(1):424-33
All:	2 reference(s)