Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Il3ram1
Name:	interleukin 3 receptor, alpha chain; mutation 1
MGI ID:	MGI:3652833
Synonyms:	Il3raA/J, Il3ran
Gene:	Il3ra  Location: Chr14:8114270-8123851 bp, - strand  Genetic Position: Chr14, 7.08 cM
Alliance:	Il3ram1 page

Strain of Origin:

multiple strains

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: Sequence analysis revealed A/J mice lack the sequence corresponding to exon 8, which encodes 10 amino acid residues in the extracellular domain. Aberrant splicing was due to a 5 base pair deletion at the branch point in intron 7. (J:23971)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 12 strains available      Cell Lines: 0 lines available
Carrying any Il3ra Mutation:	36 strains or lines available

Original:	J:23971 Ichihara M, et al., Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene. EMBO J. 1995 Mar 1;14(5):939-50
All:	3 reference(s)