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Fezf1tm1Hibi
Targeted Allele Detail
Summary
Symbol: Fezf1tm1Hibi
Name: Fez family zinc finger 1; targeted mutation 1, Masahiko Hibi
MGI ID: MGI:3626294
Synonyms: Fez-
Gene: Fezf1  Location: Chr6:23245043-23248361 bp, - strand  Genetic Position: Chr6, 10.55 cM, cytoband A3
Alliance: Fezf1tm1Hibi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107405
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A PGK-neo cassette replaced sequences encoding amino acids 1-350. (J:107405)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fezf1 Mutation:  31 strains or lines available
Notes
ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl<+>) or EB3 (129P2/OlaHsd). EB3 cells, derived from E14TG2a, carry one allele of Pou5f1 that has been inactivated via targeted integration of E14TG2a ES cells with an IRESBSDpA selection cassette. J:107405 does not mention whether the null allele of Pou5f1 is also present in the line of mice created.
References
Original:  J:107405 Hirata T, et al., Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously. Development. 2006 Apr;133(8):1433-43
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory