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Tg(Camk2a-Prkaca)426Tabe
Transgene Detail
Summary
Symbol: Tg(Camk2a-Prkaca)426Tabe
Name: transgene insertion 426, Ted Abel
MGI ID: MGI:3626071
Synonyms: CaMKII-R(AB), R(AB), R(AB)-2
Transgene: Tg(Camk2a-Prkaca)426Tabe  Location: unknown  
Alliance: Tg(Camk2a-Prkaca)426Tabe page
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Camk2a-Prkaca)426Tabe expresses 1 gene
 
Mutation detailsThe cAMP-dependent protein kinase A (PKA or PRKACA) RIalpha regulatory subunit, R(AB), was mutated at both cAMP binding sites and placed under control of the mouse Camk2a promoter. (J:38837)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:38837 Abel T, et al., Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell. 1997 Mar 7;88(5):615-26
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory