Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ppiftm1Mmos
Name:	peptidylprolyl isomerase F (cyclophilin F); targeted mutation 1, Michael A Moskowitz
MGI ID:	MGI:3624425
Synonyms:	CypDflox
Gene:	Ppif  Location: Chr14:25694578-25700892 bp, + strand  Genetic Position: Chr14, 15.06 cM
Alliance:	Ppiftm1Mmos page

Germline Transmission:	Earliest citation of germline transmission: J:101149
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     LoxP sites flank exons 3-5. (J:101149)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppif Mutation:	18 strains or lines available

Original:	J:101149 Schinzel AC, et al., Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12005-10
All:	7 reference(s)