Calcrltm1Kmca
Targeted Allele Detail
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Symbol: |
Calcrltm1Kmca |
Name: |
calcitonin receptor-like; targeted mutation 1, Kathleen M Caron |
MGI ID: |
MGI:3623122 |
Synonyms: |
Calcrl- |
Gene: |
Calcrl Location: Chr2:84160970-84255755 bp, - strand Genetic Position: Chr2, 49.38 cM
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Alliance: |
Calcrltm1Kmca page
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Generalized edema in Calcrltm1Kmca/Calcrltm1Kmca, Admtm1Unc/Admtm1Unc, and Ramp2tm1Kmca/Ramp2tm1Kmca mice
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:106927
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neomycin resistance cassette replaced exons 5 and 6, which includes the translation site, via homologous recombination. Quantitative RT-PCR confirmed absence of RNA.
(J:106927)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Calcrl Mutation: |
37 strains or lines available
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Original: |
J:106927 Dackor RT, et al., Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol. 2006 Apr;26(7):2511-8 |
All: |
5 reference(s) |
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