Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Usp14nmf375
Name:	ubiquitin specific peptidase 14; neuroscience mutagenesis facility, 375
MGI ID:	MGI:3622127
Synonyms:	NMF375
Gene:	Usp14  Location: Chr18:9993615-10030149 bp, - strand  Genetic Position: Chr18, 4.91 cM
Alliance:	Usp14nmf375 page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Hypomorph) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a T to C transition in position 4 of the splice site donor region of intron 9. Western blot anlaysis confirmed the absence of protein expression in the spinal cord without the detection of truncated proteins. Authors state that this allele is hypomorphic based on phenotypic analysis. Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Usp14 Mutation:	45 strains or lines available

Original:	J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7;
All:	2 reference(s)