Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lxntm1Yari
Name:	latexin; targeted mutation 1, Yasuyoshi Arimatsu
MGI ID:	MGI:3622076
Synonyms:	Lxn-
Gene:	Lxn  Location: Chr3:67365332-67371240 bp, - strand  Genetic Position: Chr3, 30.98 cM
Alliance:	Lxntm1Yari page

Germline Transmission:	Earliest citation of germline transmission: J:106948
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced the coding sequence in exon 1. Western blot and immunohistochemistry failed to detect protein in mutant brain samples. (J:106948)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lxn Mutation:	7 strains or lines available

Original:	J:106948 Jin M, et al., Reduced pain sensitivity in mice lacking latexin, an inhibitor of metallocarboxypeptidases. Brain Res. 2006 Feb 23;1075(1):117-21
All:	3 reference(s)