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Gene Expression Data
Assay Details
Assay
Reference: J:105958 Chen J, et al., Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1. Gene Expr Patterns. 2006 Apr;6(4):376-82
Assay type: RNA in situ
MGI Accession ID: MGI:3620818
Gene symbol: Dll3
Gene name: delta like canonical Notch ligand 3
Probe: Dll3 cDNA7
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3B, +/?: embryonic day 9.5 (more )
Note: Wild-type embryos are either heterozygotes or +/+.
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Strong 3B +/?
TS15: trunk somite Weak Regionally restricted 3B +/? Expression is in a faint band through the prospective somite above the clearly demarcated boundary with the presomitic mesoderm.
Specimen +/-: embryonic day 9.5; B4galt1tm1Shur/B4galt1+ (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Strong Expression in heterozygotes is the same as in wild-type embryos.
TS15: trunk somite Weak Regionally restricted Expression in heterozygotes is the same as in wild-type embryos. Expression is in a faint band through the prospective somite above the clearly demarcated boundary with the presomitic mesoderm.
Specimen 3B, -/-: embryonic day 9.5; B4galt1tm1Shur/B4galt1tm1Shur (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Strong 3B -/-
TS15: trunk somite Trace Regionally restricted 3B -/- Expression is lost significantly in the prospective somite.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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