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Aifm2tm1Hbsh
Targeted Allele Detail
Summary
Symbol: Aifm2tm1Hbsh
Name: apoptosis-inducing factor, mitochondrion-associated 2; targeted mutation 1, H B Shu
MGI ID: MGI:3619528
Synonyms: AMID-
Gene: Aifm2  Location: Chr10:61551042-61575039 bp, + strand  Genetic Position: Chr10, 32.27 cM
Alliance: Aifm2tm1Hbsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105660
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced part of exon 2 containing the start codon. Protein was not detected in testis, kidney or spleen of mutant mice. (J:105660)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aifm2 Mutation:  19 strains or lines available
References
Original:  J:105660 Mei J, et al., The p53-inducible apoptotic protein AMID is not required for normal development and tumor suppression. Oncogene. 2006 Feb 9;25(6):849-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory