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Fgfr1tm5Sor
Targeted Allele Detail
Summary
Symbol: Fgfr1tm5Sor
Name: fibroblast growth factor receptor 1; targeted mutation 5, Philippe Soriano
MGI ID: MGI:3619013
Gene: Fgfr1  Location: Chr8:26008808-26067819 bp, + strand  Genetic Position: Chr8, 14.12 cM
Alliance: Fgfr1tm5Sor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105920
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 4 was flanked by loxP sites via homologous recombination. Exon 4 is the first allele common to all splice variants. (J:105920)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  221 strains or lines available
References
Original:  J:105920 Hoch RV, et al., Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development. 2006 Feb;133(4):663-73
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory