Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Acaa1btm1Vnf
Name:	acetyl-Coenzyme A acyltransferase 1B; targeted mutation 1, Valerie Nicolas-Frances
MGI ID:	MGI:3617359
Synonyms:	mThB-
Gene:	Acaa1b  Location: Chr9:118977111-118986149 bp, - strand  Genetic Position: Chr9, 71.33 cM
Alliance:	Acaa1btm1Vnf page

Germline Transmission:	Earliest citation of germline transmission: J:105494
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A sequence of 2.3 kb spanning from exon 2 to intron 3 was replaced with a GFP-neo construct. Northern blot failed to detect wild-type transcript in mutants. (J:105494)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Acaa1b Mutation:	14 strains or lines available

Original:	J:105494 Chevillard G, et al., Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism. Biochimie. 2004 Nov;86(11):849-56
All:	2 reference(s)