Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol: Tdo2chky Name: tryptophan 2,3-dioxygenase; chick yellow MGI ID: MGI:3617203 Gene: Tdo2  Location: Chr3:81865719-81883035 bp, - strand  Genetic Position: Chr3, 35.97 cM Alliance: Tdo2chky page

Pale yellow coat and cataracts in the Tdo2chky/Tdo2chky Tyrc/Tyrc mouse Show the 3 phenotype image(s) involving this allele.

Strain of Origin:

Swiss

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: Whole exome sequencing of this spontaneous mutation shows it to be a C-to-T transition in the coding sequence in exon 9, which is a nonsense mutation predicted to result in a premature stop codon at arginine codon 282 (p.R282*). (J:181237, J:222308) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tdo2 Mutation:	37 strains or lines available

Original:	J:149273 Karst SY, et al., Chick yellow: Mutation on Chromosome 3 causing eye and coat color abnormalties. MGI Direct Data Submission. 2009;
All:	3 reference(s)