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Rab3ctm1Sud
Targeted Allele Detail
Summary
Symbol: Rab3ctm1Sud
Name: RAB3C, member RAS oncogene family; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:3615356
Gene: Rab3c  Location: Chr13:110190721-110417530 bp, - strand  Genetic Position: Chr13, 61.19 cM
Alliance: Rab3ctm1Sud page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105478
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exon 1, encoding residues 9-84, with a neomycin resistance cassette. Absence of protein was confirmed in immunoblot analysis of mutant brain samples. (J:105478)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rab3c Mutation:  21 strains or lines available
References
Original:  J:105478 Schluter OM, et al., A complete genetic analysis of neuronal Rab3 function. J Neurosci. 2004 Jul 21;24(29):6629-37
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory