Gene Expression Data
Assay Details
Assay
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Reference:
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J:88448
Kusumi K, et al., Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system. Mech Dev. 2001 Jan;100(1):141-4
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3611832
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Gene symbol:
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Dll3
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Gene name:
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delta like canonical Notch ligand 3
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Probe:
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Dll3 cDNA2
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Probe preparation:
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Antisense RNA
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Assay notes:
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It is possible another probe (MGI:2446514) was used in this assay.
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Results
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Specimen
1D:
embryonic day 10.75
(more )
Specimen
1D:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 10.75
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: midbrain |
Strong |
|
1D
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There is a series of bilateral and longitudinal stripes detected in the mid/hindbrain territory.
|
TS17: rhombomere |
Strong |
Regionally restricted |
1D
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There is strong expression in the rhombic lips. There is a series of bilateral and longitudinal stripes detected in the mid/hindbrain territory.
|
TS17: hindbrain roof plate |
Strong |
|
1D
|
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TS17: future spinal cord |
Present |
Regionally restricted |
1D
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There is a wide dorsal band along the spinal cord.
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Specimen
Not shown:
embryonic day 10.75
(more )
Specimen
Not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.75
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: head mesenchyme |
Absent |
|
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There is no expression in cranial neural crest or head mesodermal derivatives.
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Specimen
2A:
embryonic day 9.5
(more )
Specimen
2A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
2B:
embryonic day 9.5
(more )
Specimen
2B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Specimen
2C:
embryonic day 9.5
(more )
Note: This is a ventral view.
Specimen
2C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
whole mount
|
Note:
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This is a ventral view.
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Specimen
2D:
embryonic day 9.5
(more )
Note: This is a lateral view.
Specimen
2D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
whole mount
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Note:
|
This is a lateral view.
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Specimen
2E:
embryonic day 9.75
(more )
Note: This specimen is from a series along the A-P axis of the embryo; it is the most rostral section.
Specimen
2E:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.75
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
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Note:
|
This specimen is from a series along the A-P axis of the embryo; it is the most rostral section.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2E
|
Changes in expression reflect the temporal progression of spinal cord development. Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and domains of motor neuron differentiation.
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Specimen
2F:
embryonic day 9.75
(more )
Note: This specimen is from a series along the A-P axis of the embryo.
Specimen
2F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.75
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
section
|
Note:
|
This specimen is from a series along the A-P axis of the embryo.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2F
|
Changes in expression reflect the temporal progression of spinal cord development. Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and domains of motor neuron differentiation.
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Specimen
2G:
embryonic day 9.75
(more )
Note: This specimen is from a series along the A-P axis of the embryo.
Specimen
2G:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.75
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
|
Note:
|
This specimen is from a series along the A-P axis of the embryo.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2G
|
Changes in expression reflect the temporal progression of spinal cord development. Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and domains of motor neuron differentiation.
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Specimen
2H:
embryonic day 9.75
(more )
Note: This specimen is from a series along the A-P axis of the embryo; it is the most caudal section.
Specimen
2H:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.75
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
This specimen is from a series along the A-P axis of the embryo; it is the most caudal section.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2H
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Changes in expression reflect the temporal progression of spinal cord development. Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and domains of motor neuron differentiation.
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Specimen
2I:
embryonic day 9.75
(more )
Note: Lateral view of the embryo sectioned in 2E-H.
Specimen
2I:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.75
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
whole mount
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Note:
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Lateral view of the embryo sectioned in 2E-H.
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Specimen
2J:
embryonic day 10.25
(more )
Specimen
2J:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 10.25
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2J
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Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and ventrolateral domains of motor neuron differentiation.
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TS15: neural tube floor plate |
Absent |
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2J
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Specimen
2K:
embryonic day 9.5-10.25
(more )
Note: The exact age of the specimen was not reported.
Specimen
2K:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.5-10.25
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
|
Note:
|
The exact age of the specimen was not reported.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2K
|
Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and ventrolateral domains of motor neuron differentiation.
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TS15: neural tube floor plate |
Absent |
|
2K
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Specimen
2L:
embryonic day 9.5-10.25
(more )
Note: The exact age of the specimen was not reported.
Specimen
2L:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 9.5-10.25
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
|
Note:
|
The exact age of the specimen was not reported.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2L
|
Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and ventrolateral domains of motor neuron differentiation.
|
TS15: neural tube floor plate |
Absent |
|
2L
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Specimen
2M:
embryonic day 9.5-10.25
(more )
Note: The exact age of the specimen was not reported.
Specimen
2M:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5-10.25
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
|
Note:
|
The exact age of the specimen was not reported.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube lateral wall |
Present |
Regionally restricted |
2M
|
Expression coincides with the program of commissural neuron differentiation and is excluded from the ventricular zone and ventrolateral domains of motor neuron differentiation.
|
TS15: neural tube floor plate |
Absent |
|
2M
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Specimen
3A:
embryonic day 9.5
(more )
Specimen
3A:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
whole mount
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Specimen
3B:
embryonic day 9.75
(more )
Specimen
3B:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.75
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
whole mount
|
Specimen
3C:
embryonic day 10.0
(more )
Specimen
3C:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 10.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
whole mount
|
Specimen
3D:
embryonic day 10.25
(more )
Specimen
3D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.25
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
3E:
embryonic day 10.5
(more )
Specimen
3E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Specimen
3F:
embryonic day 9.0
(more )
Specimen
3F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Specimen
3G:
embryonic day 9.5
(more )
Specimen
3G:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
3H:
embryonic day 10.0
(more )
Specimen
3H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: rhombomere 2 |
Present |
|
3H
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Expression is present at the ventral midline, marking the developing motor neuron pools of the future Vth and VIIth nuclei.
|
TS16: rhombomere 4 |
Present |
|
3H
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Expression is present at the ventral midline, marking the developing motor neuron pools of the future Vth and VIIth nuclei.
|
TS16: rhombomere 5 |
Present |
|
3H
|
|
TS16: rhombomere 6 |
Present |
|
3H
|
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Specimen
3I:
embryonic day 10.5
(more )
Specimen
3I:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
3J:
embryonic day 11.0
(more )
Specimen
3J:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 11.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
4B Wt:
embryonic day 10.5
(more )
Specimen
4B Wt:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: hindbrain |
Present |
Regionally restricted |
4B Wt
|
Expression is present in longitudinal columns that presumably reflect the differentiation of distinct subpopulations of neurons.
|
Specimen
4B pu:
(close )
Genetic Background:
|
involves: 101/Rl * C3H/Rl
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Mutant Allele(s):
|
Dll3pu/Dll3pu
|
Age:
|
embryonic day 10.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: hindbrain |
Present |
Regionally restricted |
4B pu
|
Expression is present in longitudinal columns that presumably reflect the differentiation of distinct subpopulations of neurons. There is no difference in expression between mutant and wild type.
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