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Adora2atm1Dyj
Targeted Allele Detail
Summary
Symbol: Adora2atm1Dyj
Name: adenosine A2a receptor; targeted mutation 1, Yuan-Ji Day
MGI ID: MGI:3611746
Synonyms: A2Aflox, A2ARflox, Adora2atm1Masc, Adora2atmJyd
Gene: Adora2a  Location: Chr10:75152711-75170618 bp, + strand  Genetic Position: Chr10, 38.52 cM, cytoband B5.3
Alliance: Adora2atm1Dyj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104338
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exon 2, a critical exon, was flanked by loxP sites. (J:104338)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adora2a Mutation:  36 strains or lines available
References
Original:  J:104338 Bastia E, et al., A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization. Neuropsychopharmacology. 2005 May;30(5):891-900
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory