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Vps26atm1Cos
Targeted Allele Detail
Summary
Symbol: Vps26atm1Cos
Name: VPS26 retromer complex component A; targeted mutation 1, Frank Costantini
MGI ID: MGI:3610386
Synonyms: Hbeta58-
Gene: Vps26a  Location: Chr10:62291014-62322584 bp, - strand  Genetic Position: Chr10, 32.41 cM, cytoband B3-B5
Alliance: Vps26atm1Cos page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:102476
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exon 2 of the vacuolar protein sorting 26 homolog A gene with a neomycin(neo) resistance cassette and a polyadenylation sequence. (direct communication)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vps26a Mutation:  32 strains or lines available
References
Original:  J:102476 Griffin CT, et al., Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15173-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory