Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Apba1tm1Amor
Name:	amyloid beta precursor protein binding family A member 1; targeted mutation 1, Atsushi Mori
MGI ID:	MGI:3609568
Gene:	Apba1  Location: Chr19:23736251-23926960 bp, + strand  Genetic Position: Chr19, 18.45 cM
Alliance:	Apba1tm1Amor page

Germline Transmission:	Earliest citation of germline transmission: J:102794
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129S/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 1.0-kb sequence containing the first methionine of the gene was replaced with the pMC1-neomycin-polyA cassette. Northern and Western blot analyses failed to detect transcript and protein, respectively, in mutant brain samples. (J:102794)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apba1 Mutation:	32 strains or lines available

Original:	J:102794 Mori A, et al., Alteration of methamphetamine-induced striatal dopamine release in mint-1 knockout mice. Neurosci Res. 2002 Jul;43(3):251-7
All:	4 reference(s)