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Sostdc1tm1Nit
Targeted Allele Detail
Summary
Symbol: Sostdc1tm1Nit
Name: sclerostin domain containing 1; targeted mutation 1, Nobuyuki Itoh
MGI ID: MGI:3604658
Gene: Sostdc1  Location: Chr12:36364168-36368451 bp, + strand  Genetic Position: Chr12, 16.82 cM, cytoband B2
Alliance: Sostdc1tm1Nit page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101382
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The first two exons were replaced with an IRES-LacZ-polyA/PGK-neo cassette. (J:101382)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sostdc1 Mutation:  28 strains or lines available
References
Original:  J:101382 Kassai Y, et al., Regulation of mammalian tooth cusp patterning by ectodin. Science. 2005 Sep 23;309(5743):2067-70
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory