Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Adipor1tm1Dgen
Name:	adiponectin receptor 1; targeted mutation 1, Deltagen
MGI ID:	MGI:3604517
Gene:	Adipor1  Location: Chr1:134343116-134361089 bp, + strand  Genetic Position: Chr1, 58.22 cM, cytoband E4
Alliance:	Adipor1tm1Dgen page

Germline Transmission:	Earliest citation of germline transmission: J:122027
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in liver, gallbladder, urinary bladder, pituitary gland, adrenal gland, testis, coagulating gland, prostate gland, ovary, whole brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian glands, heart, lung, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, salivary gland, skeletal muscle, tongue, stomach, small intestine, cecum, colon, epididymis, seminal vesicle, uterus and white fat. LacZ expression was detected in testis with moderate staining observed in some spermatogenic cells of the seminiferous tubules. (J:122027)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	52 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adipor1 Mutation:	43 strains or lines available

Original:	J:122027 Bjursell M, et al., Opposing effects of adiponectin receptors 1 and 2 on energy metabolism. Diabetes. 2007 Mar;56(3):583-93
All:	19 reference(s)