Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:99531
Benedito R, et al., Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles. Gene Expr Patterns. 2005 Aug;5(6):750-5
|
|
Assay type:
|
In situ reporter (knock in)
|
|
MGI Accession ID:
|
MGI:3588062
|
|
Gene symbol:
|
Dll4
|
|
Gene name:
|
delta like canonical Notch ligand 4
|
|
|
Results
|
Specimen
1H:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more  )
Specimen
1H:
(close  )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: blood vessel |
Present |
Regionally restricted |
1H
|
Expression is in the endothelial cells of the microvessels of the neural tube.
|
Specimen
1J:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Specimen
1J:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1L:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
1L:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: heart ventricle |
Present |
Regionally restricted |
1L
|
Expression is in the endothelial cells.
|
Specimen
1M:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
1M:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
Specimen
3M:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
3M:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: olfactory epithelium |
Present |
Graded |
3M
|
Expression is higher in the basal region of the epithelium that is juxtaposed to the surrounding blood vessels.
|
Specimen
3P:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
3P:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
Specimen
4B:
embryonic day 16.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4B:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
Specimen
4C:
postnatal adult; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4C:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: intestine |
Present |
Regionally restricted |
4C
|
Expression is in the crypts with few cells in the epithelium of the villi projections.
|
| TS28: blood vessel endothelium |
Absent |
|
4C
|
Absent in the endothelium of vessels in the the villi.
|
Specimen
4E:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4E:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: thymus primordium |
Present |
Regionally restricted |
4E
|
Expression is in epithelial cells.
|
| TS23: blood vessel |
Present |
Regionally restricted |
4E
|
Expression is in a few endothelial cells of the thymus.
|
Specimen
4F:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4F:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: thymus primordium |
Present |
Regionally restricted |
4F
|
Expression is in epithelial cells.
|
| TS23: blood vessel |
Present |
Regionally restricted |
4F
|
Expression is in a few endothelial cells and is excluded from the majority of vessels in the thymus.
|
Specimen
4G:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4G:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: blood vessel |
Present |
Regionally restricted |
4G
|
Expression is in endothelial cells in some vessels of the kidney.
|
Specimen
4H:
postnatal adult; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4H:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: renal cortex |
Present |
Regionally restricted |
4H
|
Expression is higher in some of the endothelial cells of the glomeruli and very weak in the peritubular endothelium.
|
| TS28: renal medulla |
Present |
Regionally restricted |
4H
|
Expression is in the arteries.
|
Specimen
4I:
embryonic day 15.5; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4I:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: blood vessel |
Present |
Regionally restricted |
4I
|
Shown is expression in the lung endothelium.
|
Specimen
4J:
postnatal adult; Dll4tm1Jrt/Dll4 +
(more )
Note: Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
Specimen
4J:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * ICR
|
|
Mutant Allele(s):
|
Dll4tm1Jrt/Dll4+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
2% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: green - Dll4 reporter; red - Pecam1 (assay MGI:3588065).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: blood vessel |
Present |
Regionally restricted |
4J
|
Shown is expression in the lung endothelium.
|
|
Analysis Tools