Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fzd5tm1Cle
Name:	frizzled class receptor 5; targeted mutation 1, Hans Clevers
MGI ID:	MGI:3583769
Synonyms:	Fz5LoxP
Gene:	Fzd5  Location: Chr1:64769717-64776907 bp, - strand  Genetic Position: Chr1, 32.74 cM
Alliance:	Fzd5tm1Cle page

Germline Transmission:	Earliest citation of germline transmission: J:98680
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The single exon open reading frame was flanked by loxP sequences and a neomycin resistance cassette through homologous recombination. (J:98680)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fzd5 Mutation:	33 strains or lines available

Original:	J:98680 van Es JH, et al., Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol. 2005 Apr;7(4):381-6
All:	7 reference(s)