Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Senp1m1Mku
Name:	SUMO1/sentrin specific peptidase 1; mutation 1, Michael R Kuehn
MGI ID:	MGI:3582213
Synonyms:	Senp1tm1Mku
Gene:	Senp1  Location: Chr15:97936625-97991625 bp, - strand  Genetic Position: Chr15, 54.04 cM
Alliance:	Senp1m1Mku page

Germline Transmission:	Earliest citation of germline transmission: J:88845
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Transgene Type:    Transgenic Mutation:    Viral insertion   Mutation details: This allele carries a retroviral insertion in intron 1 which disrupts an intron enhancer element and resulted in a very low level of transcription of an alternatively spliced isoform lacking the carboxyl-terminal protease active site. RT-PCR revealed a significant reduction of all transcripts in mutants. (J:88845)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Senp1 Mutation:	65 strains or lines available

Original:	J:88845 Yamada S, et al., Novel testis- and embryo-specific isoforms of the phosphofructokinase-1 muscle type gene. Biochem Biophys Res Commun. 2004 Apr 2;316(2):580-7
All:	3 reference(s)