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Rac3tm1Idc
Targeted Allele Detail
Summary
Symbol: Rac3tm1Idc
Name: Rac family small GTPase 3; targeted mutation 1, Ivan de Curtis
MGI ID: MGI:3581887
Synonyms: Rac3-
Gene: Rac3  Location: Chr11:120612296-120614795 bp, + strand  Genetic Position: Chr11, 84.46 cM
Alliance: Rac3tm1Idc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99180
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ-loxP-neo-loxP cassette replaced the entire coding sequence of the gene. RT-PCR and Northern blot confirmed absence of endogenous transcript in mutant brain samples. (J:99180)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rac3 Mutation:  13 strains or lines available
References
Original:  J:99180 Corbetta S, et al., Generation and characterization of rac3 knockout mice. Mol Cell Biol. 2005 Jul;25(13):5763-76
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory