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Gene Expression Data
Assay Details
Assay
Reference: J:96874 Tsuji D, et al., Specific induction of macrophage inflammatory protein 1-alpha in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates. J Neurochem. 2005 Mar;92(6):1497-507
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3581055
Gene symbol: Ccl3
Gene name: C-C motif chemokine ligand 3
Antibody: Mip1a antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3(a): postnatal week 5 (more )
Structure Level Pattern Image Note
TS28: hippocampus Absent 3(a)
Specimen 3(b): postnatal week 5; Hexbtm1Rlp/Hexbtm1Rlp (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Single cells 3(b)
Specimen 3(c): postnatal week 15 (more )
Structure Level Pattern Image Note
TS28: hippocampus Absent 3(c)
Specimen 3(d): postnatal week 15; Hexbtm1Rlp/Hexbtm1Rlp (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Single cells 3(d)
Specimen 3(a): postnatal week 15; Hexbtm1Rlp/Hexbtm1Rlp (more )
Note: Double labeled: brown - Ccl3; red - GlcNAc.
Structure Level Pattern Image Note
TS28: brainstem Present Single cells 4(a)
Specimen 4(b): postnatal week 15; Hexbtm1Rlp/Hexbtm1Rlp (more )
Note: Double labeled: brown - Ccl3; red - Aif1 (assay MGI:3581057).
Structure Level Pattern Image Note
TS28: brainstem Present Single cells 4(b) This panel shows staining in microglia and other cells (astrocytes).
Specimen 4(c): postnatal week 15; Hexbtm1Rlp/Hexbtm1Rlp (more )
Note: Double labeled: brown - Ccl3; red - Gfap (assay MGI:3581124).
Structure Level Pattern Image Note
TS28: brainstem Present Single cells 4(c) This panel shows staining in astrocytes and other cells (microglia).
Specimen 4(d): postnatal week 15; Hexbtm1Rlp/Hexbtm1Rlp (more )
Note: Double labeled: brown - Ccl3; red - GM2.
Structure Level Pattern Image Note
TS28: brainstem Present Single cells 4(d)
Specimen not shown: postnatal week 15; Hexbtm1Rlp/Hexbtm1Rlp (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Single cells
TS28: cerebral cortex Present Single cells
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory