Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptenm1un
Name:	phosphatase and tensin homolog; m1un
MGI ID:	MGI:3578141
Synonyms:	M1un
Gene:	Pten  Location: Chr19:32734977-32803560 bp, + strand  Genetic Position: Chr19, 28.14 cM
Alliance:	Ptenm1un page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Hypomorph) Mutation:    Nucleotide substitutions   Mutation details: ENU treatment induced a T-to-A mutation changing methionine codon 134 to lysine (p.M134K). The affected residue, adjacent to the phosphatase domain, is evolutonarily conserved. The allele is thought to be hypomorphic. (J:98216) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pten Mutation:	81 strains or lines available

Original:	J:98216 Garcia-Garcia MJ, et al., Inaugural Article: Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5913-9
All:	2 reference(s)