Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Ins2*Y16A)3Ell
Name:	transgene insertion 3, John F Elliot
MGI ID:	MGI:3576273
Synonyms:	tg B:16 alanine, line F
Transgene:	Tg(Ins2*Y16A)3Ell  Location: unknown
Alliance:	Tg(Ins2*Y16A)3Ell page

Strain of Origin:

NOD/MrkTac

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Ins2*Y16A)3Ell expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note rat Ins2 (24506) Ins2  (MGI:96573)   Mutation details: This transgenic construct contains the rat insulin7 construct of the rat insulin 2 gene fused to a mutated preproinsulin II cDNA where the tyrosine at position 16 of the B chain was replaced with alanine. The transgene is expressed in pancreatic beta cells. (J:97755)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:97755 Nakayama M, et al., Establishment of native insulin-negative NOD mice and the methodology to distinguish specific insulin knockout genotypes and a B:16 alanine preproinsulin transgene. Ann N Y Acad Sci. 2004 Dec;1037:193-8
All:	8 reference(s)