Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Brsk2tm1Jrs
Name:	BR serine/threonine kinase 2; targeted mutation 1, Joshua R Sanes
MGI ID:	MGI:3575113
Synonyms:	sada-, sadaex1
Gene:	Brsk2  Location: Chr7:141503488-141557981 bp, + strand  Genetic Position: Chr7, 87.43 cM, cytoband F5
Alliance:	Brsk2tm1Jrs page

Germline Transmission:	Earliest citation of germline transmission: J:96030
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP-flanked neomycin resistance gene replaced the first coding exon. Northern blot of mutant brain samples demonstrated the lack of transcript. (J:96030)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Brsk2 Mutation:	37 strains or lines available

Original:	J:96030 Kishi M, et al., Mammalian SAD kinases are required for neuronal polarization. Science. 2005 Feb 11;307(5711):929-32
All:	6 reference(s)