Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Vipr2tm1Ajh
Name:	vasoactive intestinal peptide receptor 2; targeted mutation 1, Andrew J Harmar
MGI ID:	MGI:3574664
Synonyms:	Vipr2-, VPAC2-, VPAC2R-null
Gene:	Vipr2  Location: Chr12:116041346-116109881 bp, + strand  Genetic Position: Chr12, 62.59 cM, cytoband F2
Alliance:	Vipr2tm1Ajh page

Germline Transmission:	Earliest citation of germline transmission: J:72933
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A vector containing nls-lacZ-PA-TK-neo replaced 132 bp of sequence in exon 1, which contains the translation start site. RT-PCR confirmed ablation of wild-type transcript and no lacZ expression was detected in mutants. (J:72933)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vipr2 Mutation:	30 strains or lines available

Original:	J:72933 Goetzl EJ, et al., Enhanced delayed-type hypersensitivity and diminished immediate-type hypersensitivity in mice lacking the inducible VPAC2 receptor for vasoactive intestinal peptide. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13854-9
All:	32 reference(s)