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Cecr2Gt(pGT1)1Hemc
Gene trapped Allele Detail
Summary
Symbol: Cecr2Gt(pGT1)1Hemc
Name: CECR2, histone acetyl-lysine reader; gene trap 1, Heather E McDermid
MGI ID: MGI:3574034
Synonyms: Cecr2Gt45Bic
Gene: Cecr2  Location: Chr6:120643330-120748151 bp, + strand  Genetic Position: Chr6, 56.97 cM, cytoband D
Alliance: Cecr2Gt(pGT1)1Hemc page
Mutation
origin
Mutant Cell Line:  CT45
Germline Transmission:  Earliest citation of germline transmission: J:96325
Parent Cell Line:  CGR8 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector Type: gene trap
 
Mutation detailsThe gene trap vector including the En2 intron and Beta-geo-SV40pA fell within intron 7 or 8 of the locus, depending on alternative splicing of exon 8. It was mapped to the middle of intron 7. Mutated CT45 ES cells containing this vector were used to generate mutant mice. (J:50092, J:96325)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 39 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cecr2 Mutation:  90 strains or lines available
References
Original:  J:96325 Banting GS, et al., CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. Hum Mol Genet. 2005 Feb 15;14(4):513-24
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory