Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	H2-Obvic1
Name:	histocompatibility 2, O region beta locus; virus infectivity controller 1
MGI ID:	MGI:3573873
Gene:	H2-Ob  Location: Chr17:34457879-34464882 bp, + strand  Genetic Position: Chr17, 17.98 cM
Alliance:	H2-Obvic1 page

Strain of Origin:

I/LnJ

Allele Type:    Spontaneous (Null/knockout) Mutation:    Nucleotide substitutions   Mutation details: This I/LnJ loss-of-function variant has eight nucleotide substitutions in the 5-prime and four nucleotide substitutions in the 3-prime non-coding regions and four coding mutations that cause the amino acid substitutions S128N, V148I, L167H, and E239K. (J:254532) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any H2-Ob Mutation:	24 strains or lines available

Original:	J:60602 Golovkina TV, A novel mechanism of resistance to mouse mammary tumor virus infection. J Virol. 2000 Mar;74(6):2752-9
All:	7 reference(s)