Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Birc6tm1Nai
Name:	baculoviral IAP repeat-containing 6; targeted mutation 1, Mikihiko Naito
MGI ID:	MGI:3573859
Synonyms:	Bruce-
Gene:	Birc6  Location: Chr17:74835290-75010351 bp, + strand  Genetic Position: Chr17, 45.64 cM, cytoband E3
Alliance:	Birc6tm1Nai page

Germline Transmission:	Earliest citation of germline transmission: J:96768
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: An nlacZ and floxed neo was inserted in frame to replacee part of exon 2. Mice were crossed with cre-transgenic female mice to remove the floxed neo. Protein was not expressed in mutant embryos. (J:96768)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Birc6 Mutation:	240 strains or lines available

Original:	J:96768 Hao Y, et al., Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function. Nat Cell Biol. 2004 Sep;6(9):849-60
All:	1 reference(s)